The new administration under President Trump and Robert F. Kennedy Jr. presents a pivotal opportunity to address one of the leading causes of preventable death in the United States: smoking. By reforming the U.S. Food and Drug Administration (FDA), the administration could make it easier for smokers to access safer alternatives like e-cigarettes, heated tobacco, and oral nicotine products. This shift could save hundreds of thousands of lives annually and mark a significant step forward in public health.