Panama is currently facing a surge in the smuggling of e-cigarettes and other non-combustible devices, despite the existence of Law 315, which bans their sale and distribution. These products remain widely available and easily accessible in the country, indicating a growing demand. This revelation comes from an investigation conducted by research firm Povaddo, titled “Prevention of Illicit Trade: Non-combustible Alternatives in Panama,” carried out from November 19 to December 23, 2022. Interestingly, Panama is also preparing to host the World Health Organization’s Framework Convention on Tobacco Control (COP10) and the third session of the Meeting of the Parties (MOP3) on the Protocol to Eliminate Illicit Trade in Tobacco Products, highlighting the significance of this issue.