London’s vaping scene is undeniably one of the most dynamic and potentially rewarding in the UK. With millions of residents and a constant influx of visitors, the demand for vaping products remains strong. However, launching a vape shop in this global metropolis is a venture filled with unique challenges and opportunities shaped by the city’s sheer scale, diverse boroughs, high operational costs, and intense competition. While UK-wide vaping regulations provide a baseline, success in London hinges on a granular understanding of the local landscape. This guide, updated for 2025, drills down into the specifics of opening a vape shop in London, moving beyond generic advice to offer actionable insights for this unique market.